Niro Inc. - Solids Processing Systems, Granulation & Solution Make-up / Delivery

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Niro Inc. - Solids Processing Systems, Granulation & Solution Make-up / Delivery  Niro Inc. - Solids Processing Systems, Granulation & Solution Make-up / Delivery

Pharmaceutical Products & Services Pharmaceutical Products & Services

 

Featured products:

Spray Drying

Niro's PSD pharmaceutical spray dryer is a flexible, modern, and easy-to-handle dryer available with different levels of control systems. It dries solutions, suspensions, and emulsions into powders. It can be used as a laboratory spray dryer for testing and development work, or for batch production.

The PSD offers a choice of three atomizer systems: rotary, co-current two-fluid nozzle, and fountain two-fluid nozzle. It dries both aqueous and solvent feedstocks safely. The dryer provides excellent access and is configured to be Cleaned - In - Place (CIP).

Granulation

Aeromatic-Fielder - flexible processes, either in a high shear granulator or a fluid bed processor.

Types of Granulation:

  • Wet (high / low shear mixers, fluid bed granulation, spray drying granulation)
  • Thermoplastic (melt granulation) The High Shear granulation process is a fast homogeneous combination of active powder and excipients with a binder solution or wetting agent using a high-intensity mixing blade. Batch High Shear Granulation.
  • Mixing of dry ingredients
  • Liquid Addition
  • Wet Granulation Continuous High Shear Granulation
  • De-agglomeration of preblended powders
  • Liquid Addition and Granulation

Production Equipment: PHARMA MATRIX™ Mixer/Granulator; NICA™ M6 Mixer/Granulator

Laboratory Equipment: PHARMA MATRIX™ Compact Mixer/Granulator; NICA™ M6 Mixer / Granulator; GP1™ General Processor Fluid Bed Spray Granulation

The Spray Granulation Process Fluid bed granulation / agglomeration methods have been used for many years particularly within the pharmaceutical industry. The same product container is used as for fluid bed drying with a spray nozzle assembly fitted above the product bed. The process has three stages:

  • Mixing of the dry ingredients
  • Liquid addition and granulation
  • Drying of the granule

The top spray granulator agglomerates finer particles into larger, free flowing granulates in a one-pot process. Ingredients are mixed and pre-heated by an upward flow of heated air. Granulation occurs by spraying liquid into the fluidized powder. The granules are subsequently dried with heated air. The top spray granulator can also be used for top spray coating, layering from liquids, and instantizing.

Spray Dryer Granulator

The spray dryer granulator transforms suspensions or solutions into dry, free-flowing, dustless granules. A suspension or solution of the substance to be dried is sprayed onto warm air, simultaneously drying and agglomerating the product. Batch or continuous discharge is available in the continuous mode, the product is discharged at a controlled rate to maintain an optimum bed height.

Production Equipment: Fluid Bed Dryer / Granulator; SIROCCO™; MULTI-PROCESSOR™

Laboratory Equipment: MP-MICRO™; STREA-1™


Niro Inc.

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Address

Niro Inc. Address Niro Pharma Systems
  Niro Inc.
9165 Rumsey Road
Columbia
MD 21045
USA
Tel. +1 410 997 7010
Fax +1 410 997 5021

 


  
 
 
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